منابع مشابه
Susceptibility to lead toxicity.
Adverse effects of lead on human health have been recognized for centuries. Nevertheless , current public health measures require a greater understanding of the pathobiology of chronic low level exposure (1-3). Such considerations are related to the question of what level of lead intake is harmful and why specific clinical manifestations of lead poisoning are encountered under particular circum...
متن کاملNutritional Factors and Susceptibility to Lead Toxicity
Although the quantities of lead (Pb) to which individuals are exposed vary widely, susceptibility of an individual to the effects of a specific level of exposure is another highly important factor in development of lead toxicity. For example, susceptibility to lead toxicity can be modified by several dietary factors. Low dietary intakes of calcium or iron (20% of recommended levels) substantial...
متن کاملIndividual susceptibility to toxicity.
Individual variation in susceptibility to chemical toxicity may be due to differences in toxicokinetic patterns or effect modification. Well-documented interspecies genetic differences in susceptibility to chemicals had lead to studies of such variation also within species. Epidemiological evidence now suggests that common variations, particularly in the P-450 enzymes, may play a major role in ...
متن کاملChoreoathetosis secondary to lead toxicity.
Dra. Mariana Spitz – Rua Paulo César de Andrade 200/402 22221-090 Rio de Janeiro RJ Brasil. E-mail: [email protected] Firearm projectiles have been described, albeit rarely, as a cause of lead toxicity. The usual route of lead exposure is oral ingestion, but toxicity secondary to retained bullet fragments has been well documented. Switz et al. described the first case in 1976 – a bullet wa...
متن کاملGenetic susceptibility to lead poisoning.
Major strides have been taken in the regulation of lead intoxication in the general population, but studies using genetic markers of susceptibility to environmental toxicants raise the question of whether genes can make certain individuals more vulnerable to environmental toxins such as lead. At least three polymorphic genes have been identified that potentially can influence the bioaccumulatio...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 1972
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.720273